Peer Reviewed Articles

  1. Apsite I, Stoychev G, Zhang W, Jehnichen D, Xie J, Ionov L, Porous Stimuli-Responsive Self-Folding Electrospun Mats for 4D Biofabrication, Biomacromolecules, 2017, in press
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  3. Kumar A, Tan A, Wong J, Spagnoili JC, Lam J, Blevins BD, G N, Thorne L, Ashkan K, Xie J, Liu H, Nanotechnology for Neuroscience: Promising Approaches for Diagnostics, Therapeutics and Brain Activity Mapping, Adv. Funct. Mater., 2017; 1-30
  4. Chen H, Sun X, Wang GD, Nagata K, Hao Z, Wang A, Xie J, Shen B, LiGa5O8:Cr-based theranostic nanoparticles for imaging-guided X-ray induced photodynamic therapy of deep-seated tumors, Mater. Horiz., 2017
  5. Cowger TA, Yang Y, Rink DE, Todd T, Chen H, Shen Y, Yan Y, Xie J, Protein-Adsorbed Magnetic-Nanoparticle-Mediated Assay for Rapid Detection of Bacterial Antibiotic Resistance, Bioconjug Chem, 2017; 28(4):890-896
  6. Zhao W, Cheng R, Lim SH, Miller JR, Zhang W, Tang W, Xie J, Mao L, Biocompatible and Label-Free Separation of Cancer Cells from Cell Culture Lines from White Blood Cells in Ferrofluids, Lab Chip, 2017
  7. Chen H, Weizhong Z, Guizhi Z, Xie, J, Xiaoyuan C, Rethinking Cancer Nanotheranostics, Nature Reviews Materials, 2017; 2:1-18
  8. Zhen Z, Tang W, Wang M, Zhou S, Wang H, Wu Z, Zhonglin H, Li Z, Liu L, Xie J, Protein Nanocage Mediated Fibroblast-Activation Protein Targeted Photoimmunotherapy To Enhance Cytotoxic T Cell Infiltration and Tumor Control, Nano Letters, 2017; 17(2):862-869
  9. Wang GD, Chen H, Tang W, Lee D, Xie J, Gd and Eu Co-doped Nanoscale Metal-Organic Framework as A T1-T2 Dual-modal Contrast Agent for Magnetic Resonance Imaging, Tomography, 2016; 2(3):179-187
  10. Wang GD, Nguyen HT, Cox PB, Wang L, Nagata K, Hao S, Wang A, Li S, Chen H, Xie J. X-Ray Induced Photodynamic Therapy: A Combination of Radiotherapy and Photodynamic Therapy. Theranostics, 2016; 6(13):2295-2305
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  12. Cao J, An H, Huang X, Fu G, Zhuang R, Zhu L, Xie J, Zhang F. Monitoring of the tumor response to nano-graphene oxide-mediated photothermal/photodynamic therapy by diffusion-weighted and BOLD MRI. Nanoscale. 2016; 19(8):10152-10159
  13. Fu G, Lei Z, Yang K, Zhuang R, Xie J, Zhang F. Diffusion-weighted magnetic resonance imaging for therapy response monitoring and early treatment prediction of photothermal therapy. ACS App Materials&Interfaces . 2016; 8(8):5137-5147
  14. Tang W, Zhen Z, Wang M, Wang H, Chuang Y-J, Zhang W, Wang GD, Todd T, Cowger T, Chen H, Liu L, Li Z, Xie Jin. Red Blood Cell-Facilitated Photodynamic Therapy for Cancer Treatment. Adv Func Mater. 2016; 26(11):1757-1768
  15. Melemendis S, Jefferson A, Ruparelia N, Akhtar AM, Xie J, Allen D, Hamilton A, Larkin JR, Perez-Balderas F, Smart SC, Muschel RJ, Chen X, Sibson NR, Choudhury RP. Molecular Magnetic Resonance Imaging of Angiogenesis in vivo using Polyvalent Cyclic RGD-Iron Oxide Microparticle Conjugates. Theranostics. 2015; 5(5):515-29.
  16. Chen H, Wang GD, Sun X, Todd T, Zhang F, Xie J, Shen B. Mesoporous Silica as Nanoreactors to Prepare Gd-encapsulated Carbon Dots of Controllable Sizes and Magnetic Properties. Adv Func Mater. 2016. 26(22):3973-3982.
  17. Chen H, Wang GD, Chuang YJ, Zhen Z, Chen X, Biddinger P, Hao Z, Liu F, Shen B, Pan Z, Xie J. Nanoscintillator-Mediated X-ray Inducible Photodynamic Therapy for in vivo Cancer Treatment. Nano Letter. 2015; 15(4):2249-56.
  18. Cowger T, Tang W, Zhen Z, Hu K, Rink DE, Todd T, Wang G, Zhang W, Chen H, Xie J. Casein coated Fe5C2 nanoparticles with superior r2 relaxivity for liver-specific magnetic resonance imaging. Theranostics. 2015; 5(11):1225-1232.
  19. Chen H, Wang GD, Tang W, Todd T, Zhen Z, Tsang C, Hekmatyar K, Cowger T, Hubbard RB, Zhang W, Stickney J, Shen B, Xie J. Gd-encapsulated carbonaceous dots with efficient renal clearance for magnetic resonance imaging. Adv Mater. 2014; 26(39):6761-6. 
  20. Zhen Z, Tang W, Chuang YJ, Todd T, Zhang W, Lin X, Niu G, Liu G, Wang L, Pan Z, Chen X, Xie J. Tumor Vasculature Targeted Photodynamic Therapy for Enhanced Delivery of Nanoparticles. ACS Nano, 2014, 8(6):6004-6013.
  21. Zhen Z, Tang W, Todd T, Xie J. Ferritins as Nanoplatforms for Imaging and Drug Delivery. Expert Opinion on Drug Delivery, 2014, 29:1-10.
  22. Chuang YJ, Zhen Z, Zhang F, Mishra J, Tang W, Chen H, Liu F, Huang X, Todd T, Wang L, Chen X, Xie J and Pan Z. Photostimulable near-infrared persistent luminescent nanoprobes for ultrasensitive and longitudinal deep-tissue bio-imaging. Theranostics, 2014, 4(11):1112-22.
  23. Wang L, Tang W, Zhen Z, Chen H, Xie J, Zhao Q. Improving detection specificity of iron oxide nanoparticles (IONPs) using the SWIFT sequence with long T2 suppression. Magn Reson Imaging,2014, 32(6):671-8.
  24. Zhen, Z.; Tang, W.; Guo, C.; Chen, H.; Lin, X.; Liu, G.; Fei, B.; Chen, X.; Xu, B.; Xie, J. Ferritin Nanocages to Encapsulate and Deliver Photosensitizers for Efficient Photodynamic Therapy against Cancer. ACS Nano 2013, 7(6):4830-7.
  25. Zhen, Z.; Tang, W.; Chen, H.; Lin, X.; Todd, T.; Wang, G.; Cowger, T.; Chen, X.; Xie, J. RGD-Modified Apoferritin Nanoparticles for Efficient Drug Delivery to Tumors. ACS Nano 2013, 7(8):6988-96.
  26. Todd TJ, Zhen Z, Xie J. Ferritin nanocages: great potential as clinically translatable drug delivery vehicles? Nanomedicine (Lond). 2013, 8(10):1555-7.
  27. Tang W, Zhen Z, Yang C, Wang L, Cowger T, Chen H, Todd T, Hekmatyar K, Zhao Z, Hou Y,  and Xie J. Fe5C2 Nanoparticles with High MRI Contrast Enhancement for Tumor Imaging. Small, 2013, 26(22):1245-1249.
  28. Todd T, Zhen Z, Tang W, Chen H, Chuang Y-J, Deaton K, Pan Z, and Xie J. Iron Oxide Nanoparticle Encapsulated Diatoms for Magnetic Delivery of Small Molecules to Tumors. Nanoscale. 2013, 6(4):2073-2076.
  29. Chen, H.; Zhen, Z.; Tang, W.; Todd, T.; Chuang, Y. - J.; Wang, L.; Pan, Z.; Xie, J. Label-Free Luminescent Mesoporous Silica Nanoparticles for Imaging and Drug Delivery. Theranostics2013, 3(9):650-657.
  30. Chen H, Zhen Z, Todd T, Chu P, Xie J. Nanoparticles for Improving Cancer Diagnosis. Materials Science and Engineering: R: Reports. 2013, 74(3), 35-69.
  31. Cowger, T.; Xie, J. Polyaspartic Acid Coated Iron Oxide Nanoprobes for PET/MRI Imaging. Methods Mol. Biol. 2013, 1025, 225-35.
  32. Liu, F.; Yan, W.; Chuang, Y. - J.; Zhen, Z.; Xie, J.; Pan, Z. Photostimulated near-infrared persistent luminescence as a new optical read-out from Cr³⁺-doped LiGa₅O₈. Sci Rep 2013, 3, 1554.
  33. Ghanouni P, Behera D, Xie J, Chen X, Moseley M, Biswal S. In vivo USPIO magnetic resonance imaging shows that minocycline mitigates macrophage recruitment to a peripheral nerve injury. Mol Pain. 2012;8(1):49.
  34. Zhen Z, Xie J. Development of Manganese-Based Nanoparticles as Contrast Probes for Magnetic Resonance Imaging. Theranostics. 2012; 2:45-54.
  35. Xie J, Jon S. Magnetic nanoparticle-based theranostics. Theranostics. 2012;2:122-4.
  36. Bu L, Xie J, Chen K, Huang J, Aguilar ZP, Wang A, Sun KW, Chua MS, So S, Cheng Z, Eden HS, Shen B, Chen X. Assessment and comparison of magnetic nanoparticles as MRI contrast agents in a rodent model of human hepatocellular carcinoma. Contrast Media Mol Imaging. 2012;7(4):363-72.
  37. Huang X, Swierczewska M, Choi KY, Zhu L, Bhirde A, Park J, Kim K, Xie J, Niu G, Lee KC, Lee S, Chen X. Multiplex Imaging of an Intracellular Proteolytic Cascade by using a Broad-Spectrum Nanoquencher. Angew Chem Int Ed Engl. 2012; 51(7): 1625-1630.
  38. Xie J, Liu G, Eden H, Ai H and Chen X. Surface-Engineered Magnetic Nanoparticle Platforms for Cancer Imaging and Therapy. Acc Chem Res. 2011; 44(10):883-92.
  39. 21. Liu G, Choi KY, Bhirde A, Swierczewska M, Yin J, Lee SW, Park JH, Hong JI, Xie J, Niu G, Kiesewetter DO, Lee S, Chen X. Sticky nanoparticles: a platform for siRNA delivery by a bis(zinc(II) dipicolylamine)-functionalized,self-assembled nanoconjugate. Angew Chem Int Ed Engl. 2011; 51(2): 445-449.
  40. Zhu L, Xie J, Swierczewska M, et al. Dual-functional, receptor-targeted fluorogenic probe for in vivo imaging of extracellular protease expressions. Bioconjug Chem. 2011; 22(6):1001-5.
  41. Liu G*, Xie J* and Zhang F, et al. N-Alkyl-PEI Functional Iron Oxide Nanocluster for Efficient siRNA Delivery. *Equal contribution. Small. 2011; 7(19):2742-9. 
  42. Xing R, Zhang F, Xie J, Aronova M, Zhang G, Guo N, Huang X, Sun X, Liu G, Bryant LH, Bhirde A, Liang A, Hou Y, Leapman RD, Sun S, Chen X. Polyaspartic acid coated manganese oxide nanoparticles for efficient liver MRI. Nanoscale. 2011;3(12):4943-5. 
  43. Quan Q*, Xie J*, Gao H, et al. HSA Coated Iron Oxide Nanoparticles as Drug Delivery Vehicles for Cancer Therapy. *Equal contribution. Mol. Pharm. 2011;8(5):1669-76.
  44. Xie J, Zhang F, Aronova M, et al. Manipulating the Power of an Additional Phase:  A Flower-Like Au-Fe3O4 Optical Nanosensor for Imaging Protease Expressions In vivo. ACS Nano. 2011;5(4):3043-51.
  45. Lin X*, Xie J*, Zhu L, et al. Hybrid ferritin nanoparticles as activatable probes for tumor imaging. *Equal contribution.  Angew Chem Int Ed Engl. 2011;50(7):1569-72.
  46. Lin X*, Xie J*, Gang Niu, et al. Chimeric ferritin nanocages for multiple function loading and multimodal imaging. *Equal contribution.  Nano Letters. 2011;11(2):814-9.
  47. Zhu L, Xie J, Swierczewska M, et al. Real-time video imaging of protease expression in vivo. Theranostics 2011; 1:18-27
  48. Bhirde A, Xie J, Swierczewska M, et al. Nanoparticles for cell labeling. Nanoscale. 2011;3(1):142-53.
  49. Wang J, Xie J, Zhou X, et al. Ferritin Enhances SPIO Tracking of C6 Rat Glioma Cells by MRI. Mol Imaging Biol. 2011; 13(1):87-93.
  50. Zhang F*, Xie J*, Liu G, et al. In vivo MRI tracking of cell invasion and migration in a rat glioma model. *Equal contribution. Mol Imaging Biol. 2011;13(4):695-701 .
  51. Lin X, Xie J, Chen X. Protein-based tumor molecular imaging probes. Amino Acids. 2011;41(5):1013-36.
  52. 2004-2010

  53. Xie J, Lee S, Chen X. Nanoparticle-based theranostic agents. Adv Drug Deliv Rev. 2010;62(11):1064-79.
  54. Huang J, Bu L, Xie J, Chen K, Cheng Z, Li X and Chen X. Effects of Nanoparticle Size on Cellular Uptake and Liver MRI with Polyvinylpyrrolidone-Coated Iron Oxide Nanoparticles. ACS Nano. 2010; 4(12):7151-60.
  55. Huang J*, Xie J*, Chen K, et al. HSA coated MnO nanoparticles with prominent MRI contrast for tumor imaging. *Equal contribution. Chem Comm. 2010;46(36):6684-6.
  56. Lee S, Xie J, Chen X. Peptides and Peptide Hormones for Molecular Imaging and Disease Diagnosis. Chem Rev. 2010; 110(5):3087-3111.
  57. Xie J, Chen K, Huang J, Lee S, Wang J, Gao J, Li, X, Chen X. PET/NIRF/MRI triple functional iron oxide nanoparticles, Biomaterials. 2010; 31(11):3016-3022.
  58. Lee S, Xie J, Chen X. Peptide probes for molecular imaging. Biochemistry. 2010; 49(7):1364-1376.
  59. Xie J, Wang J, Kai Chen, Huang J, Lee S, Chen X. Human serum albumin coated iron oxide nanoparticles for efficient cell labeling. Chem Commun (Camb). 2010; 46(3):433-435.
  60. Gao J, Chen K, Xie R, Xie J, Lee, S, Peng X, Chen X. Ultrasmall Near-Infrared Non-cadmium Quantum Dots for in vivo Tumor Imaging. Small. 2010; 6(2):256-261.
  61. Gao J, Chen K, Xie R, Xie J, Yan Y, Peng X, Chen, X. In vivo tumor-targeted fluorescence imaging using near-infrared non-cadmium quantum dots. Bioconjugate Chemistry. 2010; 21(4):604-609.
  62. Chen K*, Xie J*, Xu HY, et al. Triblock copolymer coated iron oxide nanoparticle conjugate for tumor integrin targeting. *Equal contribution. Biomaterials. 2009; 30(36):6912-6919.
  63. Young KL, Xu CJ, Xie J, Sun SH. Conjugating Methotrexate to magnetite (Fe3O4) nanoparticles via trichloro-s-triazine. Journal of Materials Chemistry. 2009; 19(35):6400-6406.
  64. Xie J, Chen K, Chen X. Production, modification and bio-applications of magnetic nanoparticles gestated by magnetotactic bacteria. Nano Research. 2009; 2(4): 261-278.
  65. Niu G, Li Z, Xie J, Le Q-T, Chen X. PET imaging antibody delivery in EGFR positive head-neck squamous cell carcinoma models. Journal of Nuclear Medicine. 2009; 50(7):1116-1123.
  66. Chen K, Xie J, Chen, X. RGD-human serum albumin conjugates as efficient tumor targeting probes. Molecular Imaging. 2009; 8(2):65-73.
  67. Xie J, Huang J, Li X, Sun S, Chen X. Iron oxide nanoparticle platform for biomedical applications. Current Medicinal Chemistry. 2009; 16(10):1278-94.
  68. Wang B, Xu C, Xie J, Yang Z, Sun S. pH controlled release of chromone from chromone-Fe3O4 nanoparticles. Journal of the American Chemical Society. 2008; 130(44): 14436-14437.
  69. Xu CJ, Xie J, Kohler N, Walsh EG, Chin YE, Sun SH. Monodisperse magnetite nanoparticles coupled with nuclear localization signal peptide for cell-nucleus targeting. Chemistry-an Asian Journal. 2008; 3(3):548-552.
  70. Xu C, Xie J, Ho D, Wang C, Kohler N, Walsh EG, Morgan JR, Chin YE, Sun S. Au-Fe3O4 dumbbell nanoparticles as dual-functional probes. Angewandte Chemie-International Edition. 2008; 47(1):173-176.
  71. Xie J, Chen K, Lee HY, Xu CJ, Hsu AR, Peng S, Chen XY, Sun SH. Ultrasmall c(RGDyK)-coated Fe3O4 nanoparticles and their specific targeting to integrin alpha(v)beta(3)-rich tumor cells. Journal of the American Chemical Society. 2008; 130(24):7542-7543.
  72. Shen WF, Schrag BD, Carter MJ, Xie J, Xu CJ, Sun SH, Xiao G. Detection of DNA labeled with magnetic nanoparticles using MgO-based magnetic tunnel junction sensors. Journal of Applied Physics. 2008; 103(7): 07A306.
  73. Peng S, Xie J, Sun SH. Synthesis of Co/MFe2O4 (M=Fe, Mn) core/shell nanocomposite particles. Journal of Solid State Chemistry. 2008; 181(7):1560-1564.
  74. Lee HY, Li Z, Chen K, Hsu AR, Xu CJ, Xie J, Sun SH, Chen XY. PET/MRI dual-modality tumor imaging using arginine-glycine-aspartic (RGD)-Conjugated radiolabeled iron oxide nanoparticles. Journal of Nuclear Medicine. 2008; 49(8):1371-1379.
  75. Lee HY, Lee SH, Xu CJ, Xie J, Lee JH, Wu B, Koh AL, Wang XY, Sinclair R, Xwang S, Nishimura DG, Biswal S, Sun SH, Cho SH, Chen XY. Synthesis and characterization of PVP-coated large core iron oxide nanoparticles as an MRI contrast agent. Nanotechnology. 2008; 19(16):165101 (6pp).
  76. Chung SH, Grimsditch M, Hoffmann A, Bader SD, Xie J, Peng S, Sun S. Magneto-optic measurement of Brownian relaxation of magnetic nanoparticles. Journal of Magnetism and Magnetic Materials. 2008; 320(3-4):91-95.
  77. Xie J, Xu C, Kohler N, Hou Y, Sun S. Controlled PEGylation of monodisperse Fe3O4 nanoparticles for reduced non-specific uptake by macrophage cells. Advanced Materials. 2007; 19(20):3163-3166.
  78. Xie J, Xu CJ, Xu ZC, Hou YL, Young KL, Wang SX, Pourmond N, Sun SH. Linking hydrophilic macromolecules to monodisperse magnetite (Fe3O4) nanoparticles via trichloro-s-triazine. Chemistry of Materials. 2006; 18(23):5401-5403.
  79. Xie J, Peng S, Brower N, Pourmand N, Wang SX, Sun SH. One-pot synthesis of monodisperse iron oxide nanoparticles for potential biomedical applications. Pure and Applied Chemistry. 2006; 78(5):1003-1014.
  80. Peng S, Wang C, Xie J, Sun SH. Synthesis and stabilization of monodisperse Fe nanoparticles. Journal of the American Chemical Society. 2006; 128(33):10676-10677.
  81. Li MX, Cai P, Duan CY, Lu F, Xie J, Meng QJ. Octanuclear metallocyclic Ni(4)Fc(4) compound: Synthesis, crystal structure, and electrochemical sensing for Mg2+. Inorganic Chemistry. 2004; 43(17):5174-5176.

Book Chapters:

  1. Xie J, Gao J, Chen X. Surface modification and bioconjugation of nanoparticles. Nanoplatform-Based Molecular Imaging. Publisher: John Wiley & Sons.
  2. Gao J, Xie J, Chen X, Xu B. Synthesis of nanomaterials for molecular imaging. Nanoplatform-Based Molecular Imaging. Publisher: John Wiley & Sons.
  3. Xie J, Sun S. Chemical synthesis and surface modification of monodisperse magnetic nanoparticles. Nanomaterials: Inorganic and Bioinorganic Perspectives-Encyclopedia in Inorganic Chemistry. Publisher: John Wiley & Sons, Ltd.
  4. Lin X, Xie J, Chen X. Molecular imaging in early detection of cancer. Molecular Imaging Probes in Cancer Research. World Scientific.
  5. Xie J, Chen X. MRI in drug delivery and development. The future of biomedical imaging. Publisher: Royal Society of Chemistry.